1471:

Sixtus IV becomes pope

In his 13-year pontificate, Sixtus focused on local secular politics and made the papacy an Italian principality.

803:

Irene of Athens

1516:

Hiëronymus Bosch

Born Jerome van Aeken in Brabant, Bosch was a brilliant and imaginative artist of late medieval northern Europe. His work is characterized by powerful demonic imagery.